Set in a post-apocalyptic world of ruin and rubble, populated almost exclusively by robots, we are introduced to Casshern; a cyborg who is mostly human in appearance. Suffering from amnesia, the only thing Casshern knows about himself is that everyone wants to kill him. Having no choice, Casshern is forced to fight. As we follow Casshern through a desolate wasteland on his quest to discover his true identity, we find he is humble and seemingly invincible, and he must confront the fact that he is ultimately responsible for the complete destruction of the world.